Except the first and the second cervical vertebrate (axis and atlas), the other vertebrate have similar characteristics. So these other vertebrae are called typical vertebrae. In between the vertebrae, intervertebral space is present which is filled by fibrocartilage; this is known as intervertebral disc or disk.

BONES OF THE PELVIC GIRDLE

The pelvic girdle is the connection between the trunk and lower extremities. It is formed by:

  1. Two innominate (without name) bones, one on each side.
  2. The sacrum and coccyx in between.

Nominate bone:  It is made of three parts namely ilium, ischium, and pubis. All these three bones unite to form large cup shaped cavity on the outer surface called acetabulum.

Ilium: It is upper expanded and flat part of innominate bone.

Pubis: It is the front portion of innominate bone.

Ischium: It is the solid, broad portion at the lower and back part of innominate bone. 

BONES OF LOWER LIMB 

  • Femur: It is also called thighbone. It is the longest and strongest bone of the skeleton.
  • Patella: It is a sesamoid bone developed in the tendon of quadriceps femoris muscle.
  • Tibia: It is the innermost bone of the leg.
  • Fibula: It is the lateral or outermost bone of the leg. It is along and slender bone.

BONES OF FOOT 
Bones of foot can be classified as:

  1. Tarsal bones (7 bones).
  2. Metatarsal bones (5 bones).
  3. Phalangeal bones (14 bones).
  • Tarsal bones: There are seven tarsal bones which includes:

the talus bone (articulates with leg bones)
the calcaneus bone (heel)
the three cuneiform bones
the cuboid bone
the navicular bone

  • Calcaneum: It is the largest bone of the foot. It lies at the back of the foot. Above, it articulates with talus and in front with cuboid.
  • Talus: The talus is the second largest of the tarsal bones. It forms the central and highest point of foot. It articulates at the sides with medial  and lateral malleoli and below with calcaneum.
  • Navicular (or scaphoid): It is a disc-shaped bone. It is present in the medial aspect of foot. It lies between talus at the back and three cuneiform bones in front.
  • Cuboid: It is in the lateral aspect of foot. Behind, it articulates with calcaneum. In front, it articulates with two lateral metatarsal bones.
  • Cuneiform bones: They are three in number namely medical, intermediate and lateral cuneiform bones. Posteriorly they articulate with navicular bone. Anteriorly they articulate with three metatarsal bones. 

Metatarsal bones: They are five in number. They correspond with the five toes. All of them are long bones.

Phalanges: They are 14 bones, two for the first toe and tree of the rest.

Differences between males and females:
Males and females have slightly different skeletons, including a different elbow angle. Males have slightly thicker and longer legs and arms; females have a wider pelvis and a larger space within the pelvis, through which babies travel when they are born.

The movements at joints:
Flexion: Movements increasing the angle between two bones.
Extension: Movements decreasing the angle between two bones.
Abduction: Movement of a body part away from the median plane of the body.
Adduction: Movement of a body part toward the median plane of the body.
Rotation: Circular movement around an axis.
Dorsiflexion: Upward movement (extension) of the foot or toes or of the hand or fingers.
Plantar flexion: bending the foot or toes toward the plantar surface.
Supination (Applied to arm): Turning the palm upwards.
Pronation (Applied to arm): Turning the palm downwards.

JOINTS: 
joint is the location at which two or more bones make contact.  They are constructed to allow movement and provide mechanical support, and are classified structurally and functionally.
Synovial joints (or diarthroses, or diarthroidal joints) are the most common and most moveable type of joints in the body. As with all other joints in the body, synovial joints achieve movement at the point of contact of the articulating bones. Structural and functional differences distinguish the synovial joints from the two other types of joints in the body, with the main structural difference being the existence of a cavity between the articulating bones and the occupation of a fluid in that cavity which aids movement.

  1. Ball and socket joints, such as the shoulder and hip joints. These allow a wide range of movement.
  2. Condyloid joints (or ellipsoidal joints), such as the wrist. A condyloid joint is where two bones fit together with an odd shape (e.g. an ellipse), and one bone is concave, the other convex. Some classifications make a distinction between condyloid and ellipsoid joints.
  3. Saddle joints, such as at the thumb (between the metacarpal and carpal). Saddle joints, which resemble a saddle, permit the same movements as the condyloid joints.
  4. Hinge joints, such as the elbow (between the humerus and the ulna). These joints act like a door hinge, allowing flexion and extension in just one plane.
  5. Pivot joints, such as the elbow (between the radius and the ulna). This is where one bone rotates about another.
  6. Gliding joints (or planar joints), such as in the carpals of the wrist. These joints allow a wide variety of movement, but not much distance. they provide a full variety of movement.

 TYPES OF MUSCLES:

Cardiac

Cardiac muscle tissue forms the bulk of the wall of the heart. Like skeletal muscle tissue, it is striated (the muscle fibers contain alternating light and dark bands (striations) that are perpendicular to the long axes of the fibers). Unlike skeletal muscle tissue, its contraction is usually not under conscious control (involuntary).

Smooth

Smooth muscle tissue is located in the walls of hollow internal structures such as blood vessels, the stomach, intestines, and urinary bladder. Smooth muscle fibers are usually involuntary, and they are nonstriated (smooth). Smooth muscle tissue, like skeletal and cardiac muscle tissue, can undergo hypertrophy. In addition, certain smooth muscle fibres, such as those in the uterus, retain their capacity for division and can grow by hyperplasia.

Skeletal

Skeletal muscle tissue is named for its location – attached to bones. It is striated; that is, the fibers (cells) contain alternating light and dark bands (striations) that are perpendicular to the long axes of the fibers. Skeletal muscle tissue can be made to contract or relax by conscious control (voluntary).
Muscles in the alphabetical order
A – E
 abductor digiti minimi (in the hand), abductor digiti minimi (in the foot), abductor hallucis, abductor ossis metatarsi quinti, abductor pollicis brevis, abductor pollicis longus, adductor brevis, adductor hallucis, adductor longus, adductor magnus, adductor pollicis, anconeus, anterior scalene, articularis genus, biceps brachii, biceps femoris, brachialis, brachioradialis, buccinator, coracobrachialis, corrugator supercilii, deltoid, depressor anguli oris, depressor labii inferioris, digastric, dorsal interossei (in the hand), dorsal interossei (in the foot), extensor carpi radialis brevis, extensor carpi radialis longus, extensor carpi ulnaris, extensor digiti minimi, extensor digitorum, extensor digitorum brevis, extensor digitorum longus, extensor hallucis brevis, extensor hallucis longus, extensor indicis, extensor pollicis brevis, extensor pollicis longus

 F – L
 flexor carpi radialis, flexor carpi ulnaris, flexor digiti minimi brevis (in the hand), flexor digiti minimi brevis (in the foot), flexor digitorum brevis, flexor digitorum longus, flexor digitorum profundus, flexor digitorum superficialis, flexor hallucis brevis, flexor hallucis longus, flexor pollicis brevis, flexor pollicis longus, frontalis, gastrocnemius, geniohyoid, gluteus maximus, gluteus medius, gluteus minimus, gracilis, iliocostalis cervicis, iliocostalis lumborum, iliocostalis thoracis, illiacus, inferior gemellus, inferior oblique, inferior rectus, infraspinatus, interspinalis, intertransversi, lateral pterygoid, lateral rectus, latissimus dorsi, levator anguli oris, levator labii superioris, levator labii superioris alaeque nasi, levator palpebrae superioris, levator scapulae, long rotators, longissimus capitis, longissimus cervicis, longissimus thoracis, longus capitis, longus colli, lumbricals (in the hand), lumbricals (in the foot),

M – R
masseter, medial pterygoid, medial rectus, middle scalene, multifidus, mylohyoid, obliquus capitis inferior, obliquus capitis superior, obturator externus, obturator internus, occipitalis, omohyoid, opponens digiti minimi, opponens pollicis, orbicularis oculi, orbicularis oris, palmar interossei, palmaris brevis, palmaris longus, pectineus, pectoralis major, pectoralis minor, peroneus brevis, peroneus longus, peroneus tertius, piriformis, plantar interossei, plantaris, platysma, popliteus, posterior scalene, pronator quadratus, pronator teres, psoas major, quadratus femoris, quadratus plantae, rectus capitis anterior, rectus capitis lateralis, rectus capitis posterior major, rectus capitis posterior minor, rectus femoris, rhomboid major, rhomboid minor, risorius,

S – Z
sartorius, scalenus minimus, semimembranosus, semispinalis capitis, semispinalis cervicis, semispinalis thoracis, semitendinosus, serratus anterior, short rotators, soleus, spinalis capitis, spinalis cervicis, spinalis thoracis, splenius capitis, splenius cervicis, sternocleidomastoid, sternohyoid, sternothyroid, stylohyoid, subclavius, subscapularis, superior gemellus, superior oblique, superior rectus, supinator, supraspinatus, temporalis, tensor fascia lata, teres major, teres minor, thoracis, thyrohyoid, tibialis anterior, tibialis posterior, trapezius, triceps brachii, vastus intermedius, vastus lateralis, vastus medialis, zygomaticus major, zygomaticus minor.

PATHOLOGICAL CONDITIONS

Achondroplasia:
An abnormality in the development of cartilage results in dwarfism. In some cases it is familial but in some it may be due to chromosome abnormalities. In person suffering from achondroplasia menta, sexual and reproductive development is normal.

Osteoporosis:
Osteoporosis is a condition characterized by the loss of the normal density of bone, resulting in fragile bone. Osteoporosis leads to literally abnormally porous bone that is more compressible like a sponge, than dense like a brick. This disorder of the skeleton weakens the bone causing an increase in the risk for breaking bones (bone fracture).

Osteomalacia:
A disease characterized by a gradual softening and bending of the bones with varying severity of pain; softening occurs because the bones contain osteoid tissue that has failed to calcify because of lack of vitamin D or renal tubular dysfunction; more common in women than in men, osteomalacia often begins during pregnancy.

Rickets:
A disease due to vitamin D deficiency and characterized by overproduction and deficient calcification of osteoid tissue, with associated skeletal deformities, disturbances in growth, hypocalcemia, and sometimes tetany; usually accompanied by irritability, listlessness, and generalized muscular weakness; fractures are frequent

FRACTURES
Break in the previously normal bone (primary fracture) or previously disease bone (secondary fracture).

Fractures are classified as Simple fractures and compound fractures.

Simple Fractures: In these fractures the bone is not exposed to the external environment.
Compound fractures: In these fractures the bone is exposed to the external environment.
Management of fractures: Treatment of fractures depends on various factors like:

  1. Whether the fracture is simple or compound
  2. Whether there is any displacement of the fractured segment
  3. Age of the patient etc.

Possible methods of fracture treatment are

  1. Immobilization with external splint without reduction.
  2. Closed reduction by manipulation.
  3. Closed reduction by traction followed by immobilization with external splint or fraction.
  4. Open reduction and internal fixation.
  5. Excision of fractures segment and prosthetic replacement.

Osteomyelitis
Osteomyelitis is an infection of bone and bone marrow, usually caused by pyogenic bacteria or mycobacteria. It can be usefully subclassified on the basis of the causative organism, the route, duration and anatomic location of the infection.
Types of Osteomyelitis:

  1. Pyogenic osteomyelitis (caused by staphylococcus aureus).
  2. Tuberculous osteomyelitis.
  3. Syphilitic osteomyelitis.

Treatment includes broad spectrum antibiotics and rest; sometimes surgery may be required to drain the pus.

TUMORS OF THE BONE
Osteogenic sarcoma:
Malignant tumor of the bone in which the malignant cells directly form bone tissue. Genetic, constitutional and environmental influences may be predisposing factors.
These tumors usually arise at the ends of long bones (distal/proximal femur and proximal humerus). They spread (metastasize) via the blood steam, more commonly to the lungs.
Clinical features include local pain, tenderness and swelling. Treatment includes surgery.

Ewing’s Sarcoma:
This malignant tumor usually arises in children between the ages of 5 and 15. It usually develops in the shaft of the bone. Clinical features include painful enlarging mass, often tender, warm and swollen. With combined radiation, chemotherapy, and surgery there are 75 percent chances of survival.

Osteoarthritis (OA):
Osteoarthritis is a type of arthritis that is caused by the breakdown and eventual loss of the cartilage of one or more joints. Cartilage is a protein substance that serves as a “cushion” between the bones of the joints. Osteoarthritis is also known as degenerative arthritis. Among the over 100 different types of arthritis conditions, osteoarthritis is the most common, affecting over 20 million people in the United States.

Treatment includes NSAIDs and steroids.

Rheumatoid arthritis:
Rheumatoid arthritis (RA) is traditionally considered a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. It is a disabling and painful inflammatory condition, which can lead to substantial loss of mobility due to pain and joint destruction. RA is a systemic disease, often affecting extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs, and muscles.

Ankylosing spondylitis:
Chronic inflammatory joint disease of vertebrae and sacroiliac joints that usually occurs in males. Cause is supposed to be of autoimmune in origin. Symptoms are low backache, stiffness of movements of back. At later stages all the joints may be involved. Treatment includes steroid and analgesics.

Gouty arthritis: 
Inflammation of joints due to excessive production of uric acid (is the end product of nucleic acid metabolism) in the body.
Uric acid, which is in excess in the body, accumulates in the joints evoking in inflammatory response which destroys the articular cartilage and synovial membrane, the chief joint affected in big toe.
Clinical features during an acute attack include joint pain, fever and malaise.

Bursitis: 
The fluid filled synovial cavities enclosed by capsule is called Bursa.
Inflammation of the bursa is called bursitis.  The most common bursae involved are subdeltoid bursa, olecranon bursa and prepatellar bursa.

Ganglion:
Small multiloculated cystic lesion found in the connective tissues of joint capsule or tendon sheaths. Treatment is aspiration of the fluid or removal of the cyst.

Carpel tunnel syndrome: 
Carpal tunnel syndrome (CTS) or Median Neuropathy at the Wrist is a medical condition in which the median nerve is compressed at the wrist, leading to pain, paresthesias, and muscle weakness in the forearm and hand. A form of compressive neuropathy, CTS is more common in women than it is in men, and, though it can occur at any age, has a peak incidence around age 42. The lifetime risk for CTS is around 10% of the adult population.
Most cases of CTS are idiopathic – without known cause. Repetitive activities are often blamed for the development of CTS, along with several other possible causes. However, the correlation is often unclear. 

Systemic lupus erythematosus:
Systemic lupus erythematosus (SLE or lupus) is a chronic autoimmune disease that can be fatal, though with recent medical advances, fatalities are becoming increasingly rare. As with other autoimmune diseases, the immune system attacks the body’s cells and tissue, resulting in inflammation and tissue damage. SLE can affect any part of the body, but most often harms the heart, joints, skin, lungs, blood vessels, liver, kidneys and nervous system. The course of the disease is unpredictable, with periods of illness (called flares) alternating with remission. Lupus can occur at any age, and is most common in women, particularly of non-European descent. Lupus is treatable symptomatically, mainly with corticosteroids and immunosuppressants, though there is currently no cure. However, many people with Lupus lead long and substantial lives.

DRUGS USED IN MUSCLOSKELETAL SYSTEM
Aspirin, Salicylamide, Benorylate, Diflunisal
Phenylbutazone, Oxyphenbutazone
Indomet hacin, sulindac
Ibuprofen, Naproxen, Ketoprofen, Fenoprofen, Flurbiprofen,
Diclofenac, Tolimetin
Piroxicam, Tenoxicam
Ketorolac
Paracetamol (Acetaminophen)
Metamizol (Dippyrone), Propiphenazone
Nefopam

DRUGS USED IN RHEUMOTOID ARTHRITIS 
Gold, d-Penicillamime, Levamisole
Chloroquine or Hydroxychlorquine
Sulfasalazine corticosteroids

DRUGS USED IN GOUT
NSAID’s
Colchicine
Corticosteroids
Probenedcid
Allupurinol
Sulpinpyrazone

 ABBREVIATIONS:
ANA          : Antinuclear antibody
C1-C7        : Cervical vertebrae
Ca             : Calcium
CPK           : Creatine phosphokinase
CTS           : Carpal tunnel syndrome
DTR           : Deep tendon reflexes
EMG          : Electromyography
ESR           : Erythrocyte sedimentation rate
IM             : Intramuscular
L1-L5         : Lumbar vertebrae
LE Cell       : Lupus erythematosus cell
Ortho        : Orthopedics,
P              : Phosphorus
RA            : Rheumatoid arthritis
RF             : Rheumatoid factor
ROM          : Range of motion
SLE           : Systemic lupus erythematosus
T1-T12       : Thoracic vertebrae
TMJ           : Temporomandibular joint